Drug-Drug Interactions of Irinotecan, 5-Fluorouracil, Folinic Acid and Oxaliplatin and Its Activity in Colorectal Carcinoma Treatment
The combination of folinic acid, 5-fluorouracil, oxaliplatin and/or irinotecan (FOLFOXIRI) is the standard of care for metastatic colorectal cancer (CRC).This strategy inhibits tumor growth but provokes drug resistance and serious side effects.We po boy fest 2023 aimed to improve FOLFOXIRI by optimization of the dosing and the sequence of drug admi